Does Transdermal CBD work?

Does Transdermal CBD work?

Do you suffer from pain in localized areas of your body such as the knees, shoulders, back, or neck? A Transdermal CBD Patch may help provide long-lasting relief. This article covers everything you need to know about Transdermal CBD Patches.


What does transdermal CBD mean?

Transdermal application is when a product is applied to the skin and absorbed into the bloodstream. An example is an adhesive patch containing a medicinal substance or drug. 

Transdermal CBD Patches are often a preferred topical method because:

  • The CBD will enter the bloodstream.
  • Transdermal CBD is more effective than other topical CBD products because it enters through the skin.
  • You don't have to deal with the natural taste of CBD.
  • There is a slow release of CBD throughout the day, rather than the CBD being used up all at once like CBD oil tinctures, softgels, or edibles.

 Transdermal vs topical CBD

According to this 2015 study, scientists applied a transdermal CBD product to rats that had arthritis. After the transdermal CBD was applied, it showed significantly reduced joint swelling, limb posture scores as a rating of spontaneous pain, immune cell infiltration, and thickening of the synovial membrane in a dose-dependent manner. (1)

Transdermal CBD patches can be a convenient, natural way to help reduce pain and inflammation.


What Can Transdermal CBD patches do?

Zatural CBD bottles

CBD, scientifically known as Cannabidiol, is a cannabinoid from the cannabis plant. 

CBD supports the body's endocannabinoid system, which is responsible for: 

  • Memory
  • Sleep
  • Hunger
  • Reproductive System
  • Inflammation
  • Pain
  • Mood

CBD has been shown to assist in reducing discomfort, assisting mental health, and may improve sleep.

There are many ways to take CBD, including: 

  • CBD Oil sublingually (under the tongue)
  • CBD Softgels
  • CBD Gummies
  • CBD Smokeable
  • CBD Topicals such as:
    • CBD Hot Cream
    • CBD Massage Oils
    • CBD Salve
    • CBD Facial Serums
    • Transdermal CBD Patches

That brings us back to our topic today.

Transdermal CBD Patches are a great way to get relief from pain and inflammation consistently and steadily over a few hours or days.

Many people enjoy this method because they don't have to worry about taking CBD orally every few hours or skipping a dose when fighting against chronic pain and inflammation.


Frequently Asked Questions about Transdermal CBD Patches

Women lifting weights with Zatural CBD Patch 

How do I best apply a CBD Patch?

You want to apply your CBD patch as close to the painful area as possible.

Apply it to soft skin where there is good blood flow, such as:

  • Insides of wrists
  • Insides of arms
  • Shoulders
  • Back
  • Chest

Places to avoid applying your CBD Patch:

  • Sensitive skin, such as the face.
  • Bony areas
  • Areas of the body have lots of bending of the skin
  • Oily skin. The patch may not stick as well on oily skin.

how long do you wear a CBD patch

How long do you wear a transdermal CBD patch?

A Transdermal CBD Patch can last from a few hours to a few days. It depends on what the company selling the patch recommends. Some patches have a 12-24 hour CBD release period, whereas other products may have a longer release window.

Longer release windows don't always mean better. The patch you buy only has a specific amount of CBD in it. Say a patch with 60mg of CBD was released over 4 days, then you only get 15mg of CBD daily. Transdermal CBD patches that release 20mg of CBD within 24 hrs release all the CBD in one day

How much CBD should you take

What dose should I take?

When it comes to taking CBD it is usually recommended to consider factors like age, weight, and gender. However, when it comes to transdermal CBD, the correct dose is typically universal.

It is recommend to start with whatever dose you feel is best for you. Transdermal CBD is different from other CBD products because it only targets one area rather than providing it to the whole body, leaving it up to the body to determine where the CBD is used.

So think of it in this way. How much CBD does this specific area of my body need? CBD patches come in different strengths. If you think an area needs a lot of assistance, plan on buying a stronger milligram strength patch.

Make sure what ever CBD product you decide on follows these 7 steps to buying high quality CBD.


What is Transdermal CBD Patch best for? 

A CBD patch is most effective for a person experiencing pain and inflammation in a specific, localized part of the body. CBD patches are a great option for people who do not want to take CBD orally because they don't enjoy the taste or find it inconvenient.

Most CBD patches are waterproof, so that you can shower in them too. If you are looking for full-body relief from pain, A CBD Patch may not be the best option since they mostly provide pain to the area to which they are applied.

 Women with CBD patch while gardening

How is Transdermal CBD different from other CBD topicals?

The main difference between transdermal products and topical products are:

  • Transdermal CBD Patches absorbs into the bloodstream.
  • Topical means the product does not reach the bloodstream.
  • Transdermal CBD patches may have the most advantages depending on your reason for taking CBD.

Let's go over the pros and cons.

 Pros of Transdermal CBD patches: 

  • Discreet
  • Convenient
  • Last longer than oral forms (around 24 hours)
  • Highly bioavailable because it is absorbed directly into the bloodstream through the skin and bypasses the digestive system.
  • According to a 2018 study (2), transdermal patches are comparable to oral dosage forms.

Cons of using Transdermal CBD Patches:

  • It can cause skin irritation on sensitive skin, leaving redness or irritation.


Possible side effects of using a Transdermal CBD Patch

Some people with sensitive skin experience skin redness and irritation from using the patches. It's possible to experience an allergic reaction to the patch or CBD.

When using a transdermal CBD Patch, discontinue using if you experience the following:

Possible negative reactions to adhesive patch:

  • Severe redness or blistering
  • Itchiness
  • Rash

Possible negative reactions to CBD

  • Fatigue or drowsiness
  • Nausea or vomiting
  • Significant weight or appetite changes

 CBD patch vs CBD topical

Which is more effective, Transdermal or Topical CBD?

It may seem logical that putting CBD onto the skin would work like a transdermal CBD Patch entering the bloodstream. However, this is not true. Not all CBD is transdermal. Skin penetration enhancers must be added to create a product that allows the CBD to be absorbed past the first layer of skin into the bloodstream.

Transdermal CBD products are available in many forms. CBD applied topically may provide pain relief in a localized area but is most efficient in treating skin problems such as skin inflammation, redness, minor burns, rashes, and itching. 

Transdermal CBD products best provide localized relief from pain and inflammation as CBD enters the bloodstream. What CBD products are Transdermal? Other than Transdermal CBD Patches, Transdermal lotions and creams are also available. Skin Penetrating Enhancers are added to create a product that absorbs into the skin.

Transdermal CBD Lotions and Creams may be a better choice for individuals with fragile skin, such as older people and those with an allergy to adhesive patches.


How should you use Transdermal CBD Lotion?

You can use transdermal CBD Lotion by cleaning the area with warm water, drying the skin, and then gently rubbing Transdermal CBD Lotion until it is absorbed into the skin. You can apply the product several times throughout the day, and you should notice the effects within a few minutes of applying the product.

Old Lady using transdermal CBD lotion

Where can I find a good Transdermal CBD Patch?

Not all CBD products are created equal, so follow these simple tips to find a trustworthy, high-quality transdermal CBD Patch. The company should provide a Certificate of Analysis from a third-party lab to show that the product is pure, uncontaminated, and meets legal requirements.

The CBD is from USA-grown hemp. The United States has high standards for growing CBD, including THC content, soil purity, and highly regulated pesticide use. The company should provide a satisfaction guarantee and a generous return policy. A good company wouldn't offer this if they didn't believe a product was high quality.

Well-established brands and positive reviews can help you get a feel for what companies are trustworthy. Companies like Zatural provide pure, high-quality CBD products. Check out our Transdermal CBD Patch that is available in 10 mg and 20 mg.

 Zatural Transdermal CBD Patch 

Buy Zatural Transdermal CBD Patch

Sum it up!

A few main points to remember:

Transdermal CBD Patches are another great option to help alleviate pain and inflammation, but in a localized area and without the need to take it orally if you dislike the natural flavor of CBD. Transdermal CBD and Topical CBD are not the same as they do not both enter the bloodstream. Topical works best for treating the skin.

Transdermal products work best when applied to a local area to treat pain and inflammation. Be sure that when you shop for a CBD product, remember they are not all created equal. Be sure you know the product the fore you buy to ensure it is a pure, quality product following the above steps.


For educational purposes, only

*FDA DISCLAIMER -These statements have not been evaluated by the FDA.



(1)Hammell DC; Zhang LP; Ma F; Abshire SM; McIlwrath SL; Stinchcomb AL; Westlund KN; (n.d.). Transdermal cannabidiol reduces inflammation and pain-related behaviors in a rat model of arthritis. European journal of pain (London, England). Retrieved July 8, 2022, from

(2) Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018, September 27). Cannabinoid delivery systems for pain and inflammation treatment. Molecules (Basel, Switzerland). Retrieved July 8, 2022, from


Hi Lois, yes, you can take our CBD gummies and transdermal patch simultaneously. If you take these together, the patch will help target your back specifically, while the gummies help internally.

I normally take Zatural CBD Gummies Full Spectrum 1200 mg. Can you use the transdermal patch in conjunction with the gummies for added relief, such as my lower back?

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