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How Does The CBD Entourage Effect Work?

By Gabby Hendrickson  •  0 comments  •   3 minute read

Zatural CBD oil tincture. How does the entourage effect work with CBD?

To get the most out of your medical cannabis, this blog post is for you, understanding how and why CBD works the way it does. Allows you to make informed decisions about what products will work best for you.

This blog post discusses the entourage effect cannabidiol CBD creates when you take it, the effects of the cannabinoids, and how it works to provide users with the most effective health and wellness benefits.

What Is The Term Entourage Effect?

The term entourage CBD effect is when all the natural compounds in the cannabis sativa plant work together to make CBD and THC more effective. Together they are more likely to possibly have anti inflammatory effects and help with discomfort.

The hemp plant has over 100 cannabinoids. Cannabinoids like CBN for sleep and CBG for stress, each interact with the body's endo-cannabinoid receptors. When paired together have synergistic effects.

Terpenes, found in hemp, give it its smell and have benefits like pain relief and stress reduction. Common terpenes include limonene, terpinolene, myrcene, alpha-pinene, and beta-caryophyllene.

Flavonoids, another hemp compound, protect the plant and have antioxidant properties. When people take cannabinoids, terpenes, and flavonoids together, they enhance each other's benefits with minimal side effects. This creates what is known as the entourage effect.

How Does The Entourage Effect Work?

Women scientist looking into microscope to study the entourage effect working with CBD?

Research on this theory began with Dr. Ben-Shabat in 1998. In his paper, An Entourage Effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. 

Ben-Shabat tests the activity of several different fatty acids. Noting that the fatty acids “alone show no significant activity.” However, together had the potential to increase the biological activity of other fatty acids.

This phenomenon was coined the “entourage effect”. It is the same principle that we discuss when discussing the entourage effect CBD and other compounds in the cannabis plant.

In 2011, the entourage effect was further studied by Dr. Ethan Russo. In his paper, Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Russo expands the boundaries of the CBD entourage oil effect beyond cannabinoids. He focuses on how terpenes may play an additional role if THC is present.

Study shows the CBD entourage effect works with the human endocannabinoid system. When you use a CBD product with key cannabinoids, terpenes, and flavonoids it makes the effects stronger. This synergy maximizes the therapeutic effects of each compound.

How To Maximize The Entourage Effect: 

To maximize the entourage effect in cannabis products, it's important to consider the type of cannabis extracts you're using:

  • Full Spectrum: Contains a full cannabinoid profile, including THC, CBD, terpenes, flavonoids, vitamins, and minerals. These compounds work together to enhance the entourage effect, offering the most potent benefits.
  • Broad Spectrum: Contains CBD and other cannabinoids but no THC. While the entourage effect still occurs, it's not as strong as with Full Spectrum products because of the absence of THC.
  • CBD Isolate: Contains only CBD, with no other cannabinoids or compounds. As a result, it does not produce the entourage effect but offers focused therapeutic benefits from CBD alone.


What's the difference between Full Spectrum, Broad Spectrum, and Isolate CBD oil? How does the CBD entourage effect work?

Sum It Up!

The entourage effect takes place when the cannabinoids present in the CBD oil work synergistically with the human endocannabinoid system to maximize the benefits each cannabinoid offers.

Products like Full-Spectrum CBD will have a greater entourage effect because of the amount of cannabinoids present. The entourage effect will still take place with Broad-Spectrum CBD products, but the effects may be lesser when compared to Full-Spectrum.

Maximize your CBD experience with products that include a variety of cannabinoids beyond just CBD. Make sure to check third-party lab tests for products you are interested in to see if they have more cannabinoids and not just CBD.

 

Why Buy From Zatural?

At Zatural, our customers come first, our mission is to help increase the standard of health through natural means. And we offer CBD products with large amounts of cannabinoids to offer a high-quality CBD experience.

Our products are natural, organically grown, and handcrafted. We offer a 30-day satisfaction guarantee that allows you to return your product for a full refund if you are not satisfied.

 

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For educational purposes only

*FDA DISCLAIMER -These statements have not been evaluated by the FDA.

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